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RESEARCHER / LABORATORY SAFETY MANAGER
Founder of USCB Consulting / Shareholder of Cirqle Biomedical
My multidisciplinary research comprises the fields chemistry, biochemistry, biotechnology and biomedicine and lays at the interface between private and public research with strong emphasis on industrial collaboration. I am passionated about bringing fundamental science to the market. The fundamental research and product development shall contribute to improved resource and energy efficiency as well as human health. This incorporates the essential elements: revelation of polymer-polymer or polymer-cell interactions and polymer characterization, modification, degradation, biocompatibility and application.
Bioprocess: Anaerobic digestion
Improvement of biogas production processes by, e.g., enzymatic treatment of substrates, and waste management with the aim of biomass / lignocellulose degradation, viscosity reduction, improved substrate turnover, and establishment of circular processes combining biogas and mushroom production.
Protein- and carbohydrate based oligo- and biopolymers
I started my research by investigating the intermediates formed at industrial sugar production, leading to melanoidin polymers (Maillard reaction). Cyclodextrins formed by enzymatic treatment of starch were determined in terms of mycotoxin capture in crops. Collagen from cattle skin was chemically and physically modified to develop anti-inflammatory agents for the oral human cavity. I am inquisitive about the development of anti-fungal proteins / peptides from molluscs, acting on the inner and outer human skin, and antimicrobials on nanoscale incl. chitosan that treat microbial pathogens that are protected by mucus gel covering the mucosal epihtelium they infect.
RESEARCH INTERESTS IN BIOENGINEERING
Glycoprotein-based biopolymers
My research also focus on the fascinating human cervical mucus from the female reproduction system. We reinforce mucus by cationic polysaccharides creating a barrier to sperm cells for the development of a non-hormonal contraceptive, a medical device. We also loosening the barrier for improved sperm transport by enzymatic treatment. This includes assay development, volunteer management, and comprehensive biocompatibility studies etc. We further use human cervical mucus or mimics to select sperm in a medical device for assisted reproduction.
RECENT PUBLICATIONS
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